Sjögren's disease & overlap diseases
The contribution of salivary gland ultrasound to juvenile Sjögren disease classification: performance of a weighted scoring model
Authors' conclusion
Although the inclusion of US in the classification model did not significantly improve overall discrimination, it enhanced specificity and PPV, particularly in borderline cases.
Study context
- Population
- Patients with juvenile Sjögren's disease (jSjD) with B-mode parotid US at diagnosis
- Participants
- 17 patients
- Comparison
- Weighted scoring model including parotid US vs 2016 ACR/EULAR classic model (without US)
- Outcome
- Performance of the WS for predicting ACR/EULAR classification (≥4)
Methodological detailsretrospective, ROC analysis
- Retrospective
- ROC analysis
Performance
As reported in the abstract
Prediction of fulfilment of ACR/EULAR classification criteria
| Test or model | AUC |
|---|---|
| Weighted scoring (WS) | 0.72 |
Weighted scoring (WS)
AUC0.72
Further findings
| Outcome | WS | CM | P value |
|---|---|---|---|
| Classification performance, WS vs CMComparable overall performance | P = 0.76 | ||
| AUC | 0.85 | 0.87 | |
| Specificity | 92% | 77% | |
| PPV | 86% | 73% |
- US alone for identifying patients fulfilling ≥2 conventional items (composite score ≥2)
- 0.84 · AUC
Original publication
The contribution of salivary gland ultrasound to juvenile Sjögren disease classification: performance of a weighted scoring model. Rheumatology (Oxford). Published 9 December 2025. doi:10. 1093/ rheumatology/ keaf660
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