Osteoarthritis

Tendon involvement and its association with pain and hand function in patients with osteoarthritis of the hand

Rheumatology (Oxford)Published Cross-sectional study

Authors' conclusion

This study revealed a high frequency of tendon involvement in hand OA. Tendon involvement on US did not impact hand function or self-reported pain.

Study context

Population
Patients with hand OA and age- and sex-matched controls; extensor and flexor tendons of both hands assessed by clinical examination and US
Participants
86 vs 23
Exposure
Hand OA vs age- and sex-matched controls
  • Hand OAn = 86
  • Controln = 23reference
Outcome
Frequency of tendon involvement (tenosynovitis and tendon damage) on US and its influence on pain and hand function
Methodological detailsage- and sex-matched controls, clinical examination and US, K-means cluster analysis
  • Age- and sex-matched controls
  • Clinical examination and US
  • K-means cluster analysis

Main finding

As reported in the abstract

Involvement of one or more tendon on US

P < 0.01

Observational data: associations, not effects.

Further findings

Tendon damage on US, flexor vs extensor tendons (hand OA)

Flexor tendons
2.1%
Extensor tendons
0.9%
Flexor vs extensor
P = 0.03

Tenosynovitis on US, extensor vs flexor tendons (hand OA)

Extensor tendons
8%
Flexor tendons
0.6%
Extensor vs flexor
P < 0001

Clinical examination vs US for detecting tendon involvement

Sensitivity, patient level
81.4%
Specificity, patient level
34.6%
Sensitivity, tendon level
14.5%
Specificity, tendon level
83.8%

Cluster analysis

One cluster with more radiographic features of hand OA and more tendon damage; more tenosynovitis in cluster 2

M-SACRAH function vs tendon involvement on US

No correlation

Original publication

Tendon involvement and its association with pain and hand function in patients with osteoarthritis of the hand. Rheumatology (Oxford). Published 7 August 2024. doi:10.1093/rheumatology/keae395

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