Prevalence and classification of meniscal calcifications in the human knee
Authors' conclusion
The presence of BCP was predominant in menisci of OA individuals, whereas CPP exhibited similar prevalence in individuals with and without OA.
Study context
- Population
- Human subjects with and without knee osteoarthritis (OA); meniscal posterior horn samples (medial and lateral)82 meniscal samples
- Participants
- 41 subjects
- Exposure
- Individuals with knee OA vs deceased donors without known knee OA
- OAn = 20
- Donorsn = 21reference
- Outcome
- Occurrence of meniscal calcifications (basic calcium phosphate (BCP) and CPP)
Methodological detailshistology, Raman spectroscopy
- Histology
- Raman spectroscopy
Main finding
As reported in the abstract
Calcifications in at least one meniscus
OA
All
Donors
9.5%
95% CI 1%–30%
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| Association of Pauli score with BCP presence (OA individuals) | 2.1 (0.8–5.3) | |
| Association of Pauli score with CPP presence (whole sample) | 1.3 (1.1–1.7) | |
| 0.20.5125Odds ratio (log scale) |
| Outcome | OA | Donors |
|---|---|---|
| Calcification type among calcified menisci | ||
| BCP | 28(80%) | — not stated in the abstract |
| CPP | 5(14%) | 3(75%) |
| Both types | 2(6%) | 1(25%) |
— not stated in the abstract
Original publication
Prevalence and classification of meniscal calcifications in the human knee. Osteoarthritis Cartilage. Published 6 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →