Minimally invasive interventional procedures for osteoarthritis and inflammatory arthritis: A systematic review and meta-analysis
Authors' conclusion
minimally invasive interventional procedures can improve pain and functional status of patients affected by OA or chronic sacroiliac pain of degenerative origin.
Study context
- Population
- Patients with OA or inflammatory arthritis treated with radiofrequency ablation (RFA) or transcatheter arterial embolization (TAE) (knee, hip, foot and ankle, shoulder, hand and wrist, sacroiliac joints)111 studies (38 randomized controlled trials (RCTs), 73 non-randomized studies of interventions (NRSI))
- Comparison
- Minimally invasive interventional procedures: change from baseline
- Outcome
- Change in pain intensity (visual analog scale (VAS) 0-10) from baseline
- Follow-up
- 1 month
Methodological detailsseparate meta-analyses of RCTs and NRSI, pooled MD relative to baseline, Literature search in PubMed and Web of Science; 4599 articles retrieved, 164 included in review
- Separate meta-analyses of RCTs and NRSI
- Pooled MD relative to baseline
- Literature search in PubMed and Web of Science; 4599 articles retrieved, 164 included in review
Pooled result
As reported in the abstract
Change in pain VAS from baseline
MD (CI)
Knee RFARCTs; k = 21
−3.98(−4.41 to −3.55)
Sacroiliac joints RFARCTs; k = 8
−3.18(−3.96 to −2.39)
Knee RFANRSI; k = 23
−4.12(−4.63 to −3.61)
Knee TAENRSI; k = 7
−3.84(−4.77 to −2.92)
Hip RFANRSI; k = 2
−4.34(−4.96 to −3.71)
Shoulder RFANRSI; k = 3
−3.83(−4.52 to −3.15)
Sacroiliac joints RFANRSI; k = 14
−4.93(−5.58 to −4.28)
Further pooled results
Pain intensity at 3, 6 and 12 months
- Significant decrease in pain intensity
Functional status · all assessed timepoints
- Functional status improved
Original publication
Minimally invasive interventional procedures for osteoarthritis and inflammatory arthritis: A systematic review and meta-analysis. Semin Arthritis Rheum. Published 5 August 2024. doi:10.
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