Classification of patients with osteoarthritis through clusters of comorbidities using 633 330 individuals from Spain
Authors' conclusion
Patients with a new diagnosis of OA can be clustered into groups based on their comorbidity profile, with significant differences in 10-year mortality risk.
Study context
- Population
- Individuals with first incident diagnosis of OA of the hip, knee, ankle/foot, wrist/hand or unspecified site, 2006–2020, SIDIAP primary care database, Catalonia, Spain
- Participants
- 633,330 individuals
- Exposure
- Comorbidity clusters vs 'low-morbidity' cluster
- Outcome
- 10-year mortality risk for each identified cluster
- Follow-up
- 10 years
Methodological detailslatent class analysis, k-means, Cox proportional hazards
- Latent class analysis
- K-means
- Cox proportional hazards
Main finding
As reported in the abstract
10-year mortality
Each group vs low-morbidityAdjusted hazard ratio (95% CI)
Multimorbidity
2.19(2.15–2.23)
Metabolic syndrome
1.24(1.22–1.27)
Back/neck pain plus mental health
1.12(1.09–1.15)
Observational data: associations, not effects.
Original publication
Classification of patients with osteoarthritis through clusters of comorbidities using 633 330 individuals from Spain. Rheumatology (Oxford). Published 23 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →