Systemic sclerosis & Raynaud's

Risk of atrial fibrillation in patients with systemic sclerosis: a nationwide population-based study

Rheumatology (Oxford)Published Retrospective cohort study

Main finding · Incident AFResult — go to the resultAdjusted hazard ratio 2.095 95% CI 1.466–2.994

Authors' conclusion

Patients with SSc had a 2-fold higher risk of incident AF than controls.

Study context

Population
Patients with SSc and matched controls, Korean National Health Insurance Service database, 2010–2017, followed to 2019mean follow-up 5.2 years (s.d
Participants
2,519 vs 12,595
Exposure
SSc vs age- and sex-matched controls
  • SScn = 2,519
  • Controlsn = 12,595reference
Outcome
Incident atrial fibrillation (AF)
Methodological detailsnationwide population-based, 1:5 age- and sex-matched controls, multivariable Cox proportional hazard models
  • Nationwide population-based
  • 1:5 age- and sex-matched controls
  • Multivariable Cox proportional hazard models

Main finding

As reported in the abstract

Adjusted hazard ratio

2.095

95% CI 1.466–2.994

By group

SScvs Controls
aHR 2.095 (95% CI 1.466–2.994)

Observational data: associations, not effects.

Original publication

Risk of atrial fibrillation in patients with systemic sclerosis: a nationwide population-based study. Rheumatology (Oxford). Published 4 December 2023. doi:10.1093/rheumatology/kead651

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