Pediatric rheumatology

Reproductive health knowledge and preferences in adolescent rheumatology patients: a convergent mixed methods study

Pediatr Rheumatol Online JPublished Convergent mixed methods study

Authors' conclusion

This study identified gaps in SRH knowledge among female adolescents with susceptible RDs. Many participants are receiving SRH information from non-health care sources, but desire to have discussions on SRH with their provider.

Study context

Population
Female adolescents aged 15–21 years with systemic lupus erythematosus (SLE), undifferentiated connective tissue disease (UCTD), mixed connective tissue disease (MCTD) or an overlap disease receiving care from a pediatric rheumatologist, healthcare system in central Pennsylvania10 also interviewed
Participants
16 adolescents
Exposure
Teratogenic medication use vs no teratogenic medication use
Outcome
SRH knowledge and information sources
Methodological detailssurvey, semi-structured interviews, thematic analysis, Mann-Whitney U test, joint display
  • Survey
  • Semi-structured interviews
  • Thematic analysis
  • Mann-Whitney U test
  • Joint display

Main finding

As reported in the abstract

SRH knowledge scores (general and lupus-specific)

General sexual and reproductive health (SRH) knowledge score, teratogenic vs no teratogenic medication use (lower with teratogenic use)

2.4 vs. 2.7

Lupus-specific SRH knowledge score, teratogenic vs no teratogenic medication use (lower with teratogenic use)

3.3 vs. 4.4

Observational data: associations, not effects.

Original publication

Reproductive health knowledge and preferences in adolescent rheumatology patients: a convergent mixed methods study. Pediatr Rheumatol Online J. Published 11 November 2025. doi:10.1186/s12969-025-01165-5

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