Pediatric rheumatology

Cervical spine arthritis as initial manifestation in Juvenile Idiopathic Arthritis: a multicenter retrospective study

Pediatr Rheumatol Online JPublished Retrospective case series

Authors' conclusion

Cervical spine arthritis may be the sole initial manifestation of JIA and should be considered in children with persistent torticollis.

Study context

Population
Juvenile Idiopathic Arthritis (JIA) patients presenting with cervical spine arthritis as the first and only symptom of the disease5 oligoarticular-persistent JIA
Participants
9 patients
Outcome
Clinical characteristics, diagnostic findings, treatment and outcomes
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

Age at symptom onset (mean ± SD, years)
4.98 ± 3.08
Diagnostic delay (mean ± SD, months)
6.98 ± 9.78
Torticollis (most common presenting symptom)
88.9%
Limited cervical range of motion
77.8%
Neck pain
55.6%
C1-C2 synovitis on cervical MRI (MRI in all cases)
every patient
Subluxation on MRI
4
Escalation to TNFi
7
Surgical arthrodesis
1

Observational data: associations, not effects.

Original publication

Cervical spine arthritis as initial manifestation in Juvenile Idiopathic Arthritis: a multicenter retrospective study. Pediatr Rheumatol Online J. Published 10 November 2025. doi:10.1186/s12969-025-01161-9

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