Cervical spine arthritis as initial manifestation in Juvenile Idiopathic Arthritis: a multicenter retrospective study
Authors' conclusion
Cervical spine arthritis may be the sole initial manifestation of JIA and should be considered in children with persistent torticollis.
Study context
- Population
- Juvenile Idiopathic Arthritis (JIA) patients presenting with cervical spine arthritis as the first and only symptom of the disease5 oligoarticular-persistent JIA
- Participants
- 9 patients
- Outcome
- Clinical characteristics, diagnostic findings, treatment and outcomes
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
- Age at symptom onset (mean ± SD, years)
- 4.98 ± 3.08
- Diagnostic delay (mean ± SD, months)
- 6.98 ± 9.78
- Torticollis (most common presenting symptom)
- 88.9%
- Limited cervical range of motion
- 77.8%
- Neck pain
- 55.6%
- C1-C2 synovitis on cervical MRI (MRI in all cases)
- every patient
- Subluxation on MRI
- 4
- Escalation to TNFi
- 7
- Surgical arthrodesis
- 1
Observational data: associations, not effects.
Original publication
Cervical spine arthritis as initial manifestation in Juvenile Idiopathic Arthritis: a multicenter retrospective study. Pediatr Rheumatol Online J. Published 10 November 2025. doi:10. 1186/ s12969-025-01161-9
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