Osteoarthritis

Radiographic Changes Five Years After Treatment of Meniscal Tear and Osteoarthritic Changes

Arthritis Care Res (Hoboken)Published Secondary analysis of a randomised trial

Authors' conclusion

Subjects treated with APM had greater progression in the OARSI score because of osteophyte progression but not in the KL grade.

Study context

Population
Subjects aged 45–85 years with meniscal tear, OA changes and knee pain enrolled in a seven-center randomized trialanalysed
Participants
142 subjects
Comparison
Arthroscopic partial meniscectomy (APM) vs physical therapy (PT) for meniscal tear with OA changes
  • APMn = 100
  • PTn = 42reference
Methodological detailsmulticentre (seven centres), as-treated primary analysis, propensity score with inverse probability weighting (IPW), sensitivity analysis by randomisation group
  • Multicentre (seven centres)
  • As-treated primary analysis
  • Propensity score with inverse probability weighting (IPW)
  • Sensitivity analysis by randomisation group

Primary result

As reported in the abstract

Increase in OARSI radiographic score · 60 months

APM

4.1

mean · 95% CI 3.5–4.7

PT

2.4

mean · 95% CI 1.7–3.2

P < 0.001

Further findings

Mean

OutcomeAPMPT
Baseline OARSI radiographic score (weighted)3.8 (SD 3.5)4.0 (SD 4.9)

Sensitivity analysis by randomization group

Similar findings to the primary analysis

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Radiographic Changes Five Years After Treatment of Meniscal Tear and Osteoarthritic Changes. Arthritis Care Res (Hoboken). Published 4 October 2023. doi:10.1002/acr.25197

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