Associations between anterior knee pain and 2-year patellofemoral cartilage worsening: The MOST study
Main finding · Worsening cartilage damage, lateral PF compartmentResult — go to the resultRelative risk 1.78 95% CI 1.21–2.62Authors' conclusion
Frequent AKP at baseline was associated with worsening cartilage damage in the lateral PF joint over 2 years.
Study context
- Population
- Individuals with or at risk for knee osteoarthritis (OA) from the Multicenter Osteoarthritis Study, excluding bilateral knee replacements, arthritis other than OA and radiographic patellofemoral osteoarthritis (PFOA)one knee per participant
- Participants
- 1,083 individuals
- Exposure
- Frequent anterior knee pain vs no frequent anterior knee pain
- Outcome
- Worsening PF cartilage damage (increase in magnetic resonance imaging (MRI) Osteoarthritis Knee Score)
- Follow-up
- 2 years
Methodological detailslog-binomial models
- Log-binomial models
Main finding
As reported in the abstract
Worsening cartilage damage, lateral PF compartment
Relative risk
1.78
95% CI 1.21–2.62
Frequent AKPvs No frequent AKP
RR 1.78 (95% CI 1.21–2.62)
Observational data: associations, not effects.
Further findings
Worsening cartilage damage, medial patellofemoral (PF) joint · 2 years
- No association between frequent anterior knee pain (AKP) and worsening in the medial PF joint
Baseline prevalence of frequent AKP and frequent isolated AKP
- Frequent AKP
- 14.5%
- Frequent isolated AKP
- 3.6%
Original publication
Associations between anterior knee pain and 2-year patellofemoral cartilage worsening: The MOST study. Osteoarthritis Cartilage. Published 30 September 2023. doi:10.
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