Association of knee and hip osteoarthritis with the risk of falls and fractures: a systematic review and meta-analysis
Authors' conclusion
Symptomatic knee and hip OA were both associated with an increased risk of recurrent falls, and radiographic knee OA was associated with an increased risk of falls. No statistically significant associations of radiographic and symptomatic knee or hip OA with fractures were found.
Study context
- Population
- Studies of knee and hip osteoarthritis (OA) and falls, recurrent falls and fractures, databases searched from inception to February 2023
- Participants
- 862,849 participants17 studies
- Comparison
- Symptomatic and radiographic knee and hip OA vs no OA
- Outcome
- Falls, recurrent falls and fractures
Methodological detailsrandom-effects models, Newcastle-Ottawa Scale risk of bias
- Random-effects models
- Newcastle-Ottawa Scale risk of bias
Pooled result
As reported in the abstract
Recurrent falls, falls and fractures by OA type (pooled OR)
- Symptomatic knee OA, recurrent falls: OR 1.55, 95% CI 1.10 to 2.18
- Symptomatic hip OA, recurrent falls: OR 1.50, 95% CI 1.28 to 1.75
- Symptomatic knee and hip OA not associated with falls or fractures
- Radiographic knee OA, falls: OR 1.28, 95% CI 1.03 to 1.59
- Radiographic knee OA, recurrent falls (not significant): OR 1.39, 95% CI 0.97 to 1.97
- Radiographic knee OA, fractures (not significant): OR 1.22, 95% CI 0.99 to 1.52
- Radiographic hip OA, recurrent falls (decreased): OR 0.70, 95% CI 0.51 to 0.96
- Radiographic hip OA, fractures (not significant): OR 1.16, 95% CI 0.79 to 1.71
- 2 studies at high risk of bias
- Falls self-reported in 7/8 (87.5%) and fractures in 5/11 (45.5%) of studies
Original publication
Association of knee and hip osteoarthritis with the risk of falls and fractures: a systematic review and meta-analysis. Arthritis Res Ther. Published 29 September 2023. doi:10.
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