Association Between Structural Change Over Eighteen Months and Subsequent Symptom Change in Middle‐Aged Patients Treated for Meniscal Tear
Primary result · Change in KOOS pain score, 18 to 60 monthsResult — go to the resultDifference 0.45 points 95% CI −4.45 to 5.35Authors' conclusion
We did not observe clinically important associations between early changes in cartilage damage and other structural measures and worsening in pain over the subsequent 3.5 years.
Study context
- Population
- Subjects ages ≥45 years with knee pain, cartilage damage and meniscal tear in the MeTeOR trial of arthroscopic partial meniscectomy (APM) vs physical therapycomplete magnetic resonance imaging (MRI) and KOOS data
- Participants
- 168 participants
- Comparison
- Worst vs best tertile of cartilage surface area damage score progression
Methodological detailscohort analysis of trial data, exposure tertiles
- Cohort analysis of trial data
- Exposure tertiles
Primary result
Change in KOOS pain score, 18 to 60 months
Difference
0.45 points
95% CI −4.45 to 5.35
WORST TERTILEvs BEST TERTILE
difference 0.45 points (95% CI −4.45 to 5.35)
As reported in the abstract
Further findings
Changes in bone marrow lesions, osteophytes or synovitis and subsequent pain
- No clinically important associations
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Association Between Structural Change Over Eighteen Months and Subsequent Symptom Change in Middle‐Aged Patients Treated for Meniscal Tear. Arthritis Care Res (Hoboken). Published 21 October 2022. doi:10. 1002/ acr. 24796
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