Osteoarthritis

Association Between Structural Change Over Eighteen Months and Subsequent Symptom Change in Middle‐Aged Patients Treated for Meniscal Tear

Arthritis Care Res (Hoboken)Published Secondary analysis of the Meniscal Tear in Osteoarthritis Research (MeTeOR) randomised trial

Primary result · Change in KOOS pain score, 18 to 60 monthsResult — go to the resultDifference 0.45 points 95% CI −4.45 to 5.35

Authors' conclusion

We did not observe clinically important associations between early changes in cartilage damage and other structural measures and worsening in pain over the subsequent 3.5 years.

Study context

Population
Subjects ages ≥45 years with knee pain, cartilage damage and meniscal tear in the MeTeOR trial of arthroscopic partial meniscectomy (APM) vs physical therapycomplete magnetic resonance imaging (MRI) and KOOS data
Participants
168 participants
Comparison
Worst vs best tertile of cartilage surface area damage score progression
Methodological detailscohort analysis of trial data, exposure tertiles
  • Cohort analysis of trial data
  • Exposure tertiles

Primary result

Change in KOOS pain score, 18 to 60 months

Difference

0.45 points

95% CI −4.45 to 5.35

WORST TERTILEvs BEST TERTILE
difference 0.45 points (95% CI −4.45 to 5.35)

As reported in the abstract

Further findings

Changes in bone marrow lesions, osteophytes or synovitis and subsequent pain

No clinically important associations

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Association Between Structural Change Over Eighteen Months and Subsequent Symptom Change in Middle‐Aged Patients Treated for Meniscal Tear. Arthritis Care Res (Hoboken). Published 21 October 2022. doi:10.1002/acr.24796

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