Changes in physical activity and the association between pain and physical activity – a longitudinal analysis of 17,454 patients with knee or hip osteoarthritis from the GLA:D® registry
Authors' conclusion
In low active knee or hip OA patients, a third of patients participating in an education and exercise therapy program reached and maintained at least a moderate physical activity level for 1 year. The improvement in physical activity was not dependent on pain reduction.
Study context
- Population
- Patients with knee/hip OA in the GLA:D® registry following an 8-week education and exercise therapy program4,836 low activity at baseline
- Participants
- 17,454 patients
- Exposure
- Low activity vs All
- Alln = 17,454
- Outcome
- Change in physical activity level (UCLA activity scale 1-10: low 1-4, moderate 5-6, high 7-10)
- Follow-up
- Immediately after completion and 12 months
Methodological detailsasymmetric fixed effects regression models
- Asymmetric fixed effects regression models
Main finding
As reported in the abstract
Reached or maintained at least moderate physical activity level at follow-ups
Observational data: associations, not effects.
Further findings
Association of clinically relevant change in pain (≥15 mm VAS) with increased physical activity, baseline to 12 months
- Low activity: pain improvement, β
- 1.44, P < 0.001
- Low activity: pain worsening, β
- 1.18, P < 0.001
- All patients: pain improvement, β
- 0.51, P < 0.001
- All patients: pain worsening, β
- 0.11, P = 0.215
Original publication
Changes in physical activity and the association between pain and physical activity – a longitudinal analysis of 17,454 patients with knee or hip osteoarthritis from the GLA:D® registry. Osteoarthritis Cartilage. Published 19 October 2022. doi:10.
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