Osteoarthritis

The KNee OsteoArthritis Prediction (KNOAP2020) challenge: An image analysis challenge to predict incident symptomatic radiographic knee osteoarthritis from magnetic resonance imaging (MRI) and X-ray images

Osteoarthritis CartilagePublished Diagnostic accuracy study

Authors' conclusion

The KNOAP2020 challenge established a benchmark for predicting incident symptomatic radiographic knee osteoarthritis.

Study context

Population
Test set of knees from the PROOF study (overweight females) with baseline MRI, X-ray and clinical risk factors
Participants
423 knees
Comparison
Submitted prediction models for incident symptomatic radiographic knee OA within 78 months
Outcome
Prediction of incident symptomatic radiographic knee OA (combined ACR criteria), assessed by ROCAUC and balanced accuracy (BACC)
Follow-up
78 months
Methodological detailsimage analysis challenge, blinded ground truth, Most algorithms trained on Osteoarthritis Initiative data
  • Image analysis challenge
  • Blinded ground truth
  • Most algorithms trained on Osteoarthritis Initiative data

Performance

As reported in the abstract

Model performance
Test or modelROCAUCBalanced accuracy (BACC)
Highest ROCAUC model0.64 (95% CI: 0.57-0.70)
Highest BACC model0.59 (95% CI: 0.52-0.65)

ROCAUC

Highest ROCAUC model0.64 (95% CI: 0.57-0.70)
Highest BACC model— not stated in the abstract

Balanced accuracy (BACC)

Highest ROCAUC model— not stated in the abstract
Highest BACC model0.59 (95% CI: 0.52-0.65)

Original publication

The KNee OsteoArthritis Prediction (KNOAP2020) challenge: An image analysis challenge to predict incident symptomatic radiographic knee osteoarthritis from MRI and X-ray images. Osteoarthritis Cartilage. Published 12 October 2022. doi:10.1016/j.joca.2022.10.001

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