Baseline knee extension may be associated with volumetric cartilage loss in the anterolateral tibia: data from the Osteoarthritis Initiative
Main finding · Denuded bone in anterolateral tibia (%)Result — go to the resultβ 1.702 CI 0.634–2.770Authors' conclusion
While causation cannot be determined in this study, limitation in knee extension was statistically associated with the percentage of denuded bone in the anterolateral tibia.
Study context
- Population
- Patients with knee OA, Osteoarthritis Initiative
- Participants
- 596 patients
- Exposure
- Participants with vs without knee flexion contracture
- Outcome
- Percentage of denuded bone (0 mm cartilage thickness) in the anterolateral tibia
Methodological detailslinear models, quantitative 3-Tesla MRI
- Linear models
- Quantitative 3-Tesla MRI
Main finding
Denuded bone in anterolateral tibia (%)
β
1.702
CI 0.634–2.770
By group
As reported in the abstract
Observational data: associations, not effects.
Further findings
Knee extension and anterolateral tibia denuded bone (correlation)
- R
- 0.16
- P
- P < 0.001
Lost knee extension and % denuded bone, anterolateral tibia (adjusted)
- β
- 0.261 (95% CI 0.134, 0.388)
- Adjusted for demographics, knee alignment, and OA severity
Original publication
Baseline knee extension may be associated with volumetric cartilage loss in the anterolateral tibia: data from the Osteoarthritis Initiative. Rheumatology (Oxford). Published 30 September 2022. doi:10.
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