Lupus & antiphospholipid syndrome
Racial differences in persistent glucocorticoid use patterns among medicaid beneficiaries with incident systemic lupus erythematosus
Authors' conclusion
Black, Hispanic, and Asian (vs. White) individuals had higher odds of persistently high-dose steroid use.
Study context
- Population
- Medicaid beneficiaries 18–65 years with incident systemic lupus erythematosus (SLE) who received steroids for 12 months following the index date≥1 dispensed steroid prescription
- Participants
- 6,314 beneficiaries
- Exposure
- Black, Hispanic and Asian vs White individuals
- Outcome
- Odds of belonging to the higher vs lowest steroid dose trajectories over time
- Follow-up
- 12 months
Methodological detailsgroup-based trajectory modeling, multinomial logistic regression
- Group-based trajectory modeling
- Multinomial logistic regression
Main finding
As reported in the abstract
Highest vs lowest steroid trajectory (adjusted multinomial models)
Each group vs whiteOdds ratio (95% CI)
Black
2.07(1.65–2.61)
Hispanic
1.81(1.38–2.39)
Asian
2.42(1.53–3.83)
Observational data: associations, not effects.
Further findings
Mean prednisone-equivalent dose
>5 outpatient visits at baseline and persistently high-dose steroid trajectory
| OR (95% CI) | ||
|---|---|---|
| >5 outpatient visits | 0.77 (0.60–0.98) | |
| 0.512Odds ratio (log scale) |
Original publication
Racial differences in persistent glucocorticoid use patterns among medicaid beneficiaries with incident systemic lupus erythematosus. Semin Arthritis Rheum. Published 25 October 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →