Pediatric rheumatology

A quantitative comparison between the essential medicines for rheumatic diseases in children and young people in Africa and the WHO model list

Pediatr Rheumatol Online JPublished Cross-sectional study

Authors' conclusion

Four countries (8.5%) in Africa have updated their National Essential Medicines Lists to reflect adequate care for children and young people with rheumatic diseases.

Study context

Population
National Essential Medicines Lists of the 54 countries of the WHO Africa region, medicines for rheumatic diseases in children and young people47 with a national list
Participants
54 participants
Exposure
National Essential Medicines Lists of WHO Africa region countries vs the 2021 WHO EML and WHO EML for children
Outcome
Percentage similarity of national lists with the WHO EML for rheumatic diseases in children and young people
Methodological detailsdocument review of National Essential Medicines Lists, multiple linear regression
  • Document review of National Essential Medicines Lists
  • Multiple linear regression

Main finding

As reported in the abstract

Countries with a National Essential Medicines List
47
Countries with no medicines listed for rheumatic diseases
11
Majority of countries had ≤50% similarity with the WHO EML; number of medicines, median (IQR)
3 (1- 4)
Most common medicines: MTX, SSZ and AZA; etanercept available in countries
6
Countries with only acetylsalicylic acid listed under 'Juvenile Joint diseases'
7
Countries with lists updated to reflect adequate care
4 (8.5%)

Observational data: associations, not effects.

Further findings

Predictors of the number of medicines on national lists (multiple linear regression)

Variability predicted by health expenditure per capita, socio-demographic index and availability of rheumatology services
20%, p = 0.006
Socio-demographic index
P = 0.035, 95% CI 0.64-16.16
Availability of rheumatology services (adult and/or paediatric)
P = 0.033, 95% CI 0.13 - 2.90

Original publication

A quantitative comparison between the essential medicines for rheumatic diseases in children and young people in Africa and the WHO model list. Pediatr Rheumatol Online J. Published 4 July 2024. doi:10.1186/s12969-024-00997-x

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