Pediatric rheumatology

Disease-Tailored Brief Intervention for Alcohol Use Among Youths With Chronic Medical Conditions: A Secondary Analysis of a Randomized Clinical Trial

JAMA Netw OpenPublished Secondary analysis of the Take Good Care (TGC) randomised trial

Primary result · Frequency of alcohol use (days), baseline to 12 months, high-risk alcohol use subgroup (n=52)Result — go to the resultAdjusted relative rate ratio 0.60 95% CI 0.38–0.94

Authors' conclusion

In this trial of a brief chronic illness-tailored preventive intervention, medically vulnerable youths with a high risk of alcohol use and harm decreased alcohol use.

Study context

Population
Youths aged 14–18 years with a chronic medical condition (e.g. type 1 diabetes, JIA, inflammatory bowel disease), US; subgroups with baseline high-risk vs no or low-risk alcohol use410 at 12-month follow-up
Participants
451 participants
Comparison
Self-administered, tablet-based disease-tailored TGC intervention vs treatment as usual, by baseline alcohol-use risk
Primary endpoint
Self-reported frequency of alcohol use (days) over the past 3 months
Follow-up
Up to 12 months
Methodological detailsprespecified secondary analysis, 2-group, parallel, Maximum likelihood methods using all available data, assuming missing at random
  • Prespecified secondary analysis
  • 2-group
  • Parallel
  • Maximum likelihood methods using all available data, assuming missing at random

Primary result

As reported in the abstract

Frequency of alcohol use (days), baseline to 12 months, high-risk alcohol use subgroup (n=52)

Adjusted relative rate ratio

0.60

95% CI 0.38–0.94

By group

TGCvs TAU
adjusted relative rate ratio 0.60 (95% CI 0.38–0.94)

Original publication

Disease-Tailored Brief Intervention for Alcohol Use Among Youths With Chronic Medical Conditions: A Secondary Analysis of a Randomized Clinical Trial. JAMA Netw Open. Published 1 July 2024. doi:10.1001/jamanetworkopen.2024.19858

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.