Disease-Tailored Brief Intervention for Alcohol Use Among Youths With Chronic Medical Conditions: A Secondary Analysis of a Randomized Clinical Trial
Primary result · Frequency of alcohol use (days), baseline to 12 months, high-risk alcohol use subgroup (n=52)Result — go to the resultAdjusted relative rate ratio 0.60 95% CI 0.38–0.94Authors' conclusion
In this trial of a brief chronic illness-tailored preventive intervention, medically vulnerable youths with a high risk of alcohol use and harm decreased alcohol use.
Study context
- Population
- Youths aged 14–18 years with a chronic medical condition (e.g. type 1 diabetes, JIA, inflammatory bowel disease), US; subgroups with baseline high-risk vs no or low-risk alcohol use410 at 12-month follow-up
- Participants
- 451 participants
- Comparison
- Self-administered, tablet-based disease-tailored TGC intervention vs treatment as usual, by baseline alcohol-use risk
- Primary endpoint
- Self-reported frequency of alcohol use (days) over the past 3 months
- Follow-up
- Up to 12 months
Methodological detailsprespecified secondary analysis, 2-group, parallel, Maximum likelihood methods using all available data, assuming missing at random
- Prespecified secondary analysis
- 2-group
- Parallel
- Maximum likelihood methods using all available data, assuming missing at random
Primary result
As reported in the abstract
Frequency of alcohol use (days), baseline to 12 months, high-risk alcohol use subgroup (n=52)
Adjusted relative rate ratio
0.60
95% CI 0.38–0.94
By group
TGCvs TAU
adjusted relative rate ratio 0.60 (95% CI 0.38–0.94)
Original publication
Disease-Tailored Brief Intervention for Alcohol Use Among Youths With Chronic Medical Conditions: A Secondary Analysis of a Randomized Clinical Trial. JAMA Netw Open. Published 1 July 2024. doi:10. 1001/ jamanetworkopen. 2024. 19858
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