Pediatric rheumatology

Body mass index is associated with health-related quality of life and disease characteristics in young adults with juvenile idiopathic arthritis

Pediatr Rheumatol Online JPublished Cross-sectional study

Authors' conclusion

We discovered that BMI was significantly related to HRQoL, disease activity, and disability.

Study context

Population
Young adults with juvenile idiopathic arthritis (JIA), newly diagnosed and recruited consecutively 1997–2000 in specific regions in the Nordic countries, seen at the 18-year follow-up visit72% female
Participants
355 adults
Exposure
Body mass index (BMI) groups
Outcome
Impact of BMI on HRQoL (SF-36), disease activity and disability
Follow-up
18-year follow-up
Methodological detailssub-study of the population-based Nordic JIA cohort study, 18-year follow-up visit, adjusted for sex, age, and JIA subtype
  • Sub-study of the population-based Nordic JIA cohort study
  • 18-year follow-up visit
  • Adjusted for sex, age, and JIA subtype

Main finding

As reported in the abstract

Relationship of BMI with JIA category, disease activity, disability, pain, fatigue, sleep quality and HRQoL
JIA categories vs BMI groups, significant relationship
p = 0.014
BMI vs disease activity scores (DAS28), significant relationship
p = 0.028
BMI vs disability, significant relationship
p < 0.001
BMI vs pain, significant relationship
p = 0.013
BMI vs fatigue, significant relationship
p = 0.035
BMI vs sleep quality, significant relationship
p = 0.044
BMI vs health-related quality of life (HRQoL) bodily pain, significant relationship (adjusted for sex, age, JIA subtype)
p = 0.010
BMI vs HRQoL general health, significant relationship (adjusted for sex, age, JIA subtype)
p = 0.048

Observational data: associations, not effects.

Original publication

Body mass index is associated with health-related quality of life and disease characteristics in young adults with juvenile idiopathic arthritis. Pediatr Rheumatol Online J. Published 2 February 2024. doi:10.1186/s12969-023-00931-7

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