Clinical Characteristics of Adolescents With Juvenile Idiopathic Arthritis Transitioning to Adult Rheumatology Care in Canada: Results From the Canadian Alliance of Pediatric Rheumatology Investigators (CAPRI) Registry
Authors' conclusion
A substantial proportion of youth with JIA transitioning to adult care in Canada had a high disease burden, which was reflected by their degree of disease activity, joint damage, or ongoing medication use.
Study context
- Population
- Registry participants with juvenile idiopathic arthritis (JIA) who turned 17 years between February 2017 and November 2021, transitioning to adult care in Canadaquestionnaire completed for 80
- Participants
- 131 participants
- Outcome
- Disease activity at last pediatric rheumatology visit
- Follow-up
- Last recorded pediatric rheumatology visit
Methodological detailsCAPRI JIA registry, multicentre
- CAPRI JIA registry
- Multicentre
Main finding
As reported in the abstract
Inactive disease
88
67%
Active disease
42
32%
On medications
96
73%
On bDMARDs
41
31%
Observational data: associations, not effects.
Further findings
Cumulative disease-related damage and complications by age 17 (questionnaire subset) · age 17 years
- Clinically detected joint damage
- 26%
- Joint damage on imaging
- 31%
- Uveitis
- 14%
- 80 participants with completed questionnaire
Disease activity course during final year before transfer
- In remission
- 44.2%
- Attained inactive disease
- 28.4%
- Became or remained active
- 27.4%
- Mean PRO scores stable overall; a minority reported marked worsening
Safety
At least 1 serious adverse event by age 17 · age 17 years
- At least 1 serious adverse event
- 7.5%
- 80 participants with completed questionnaire
Original publication
Clinical Characteristics of Adolescents With Juvenile Idiopathic Arthritis Transitioning to Adult Rheumatology Care in Canada: Results From the CAPRI Registry. J Rheumatol. Published 1 February 2024. doi:10.
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