Developing consensus outcome measures in juvenile systemic sclerosis: a global survey of pediatric rheumatologists and literature review
An erratum to this article was published (Pediatr Rheumatol Online J, 23 Jun 2025 ↗)
Authors' conclusion
We found significant variability in JSSc assessment and treatment preferences, influenced by geography and income.
Study context
- Population
- Pediatric rheumatologists from 26 countries; juvenile systemic sclerosis (JSSc) management
- Participants
- 141 participants26 countries
- Exposure
- Practices compared by region and country income level
- Outcome
- JSSc cardiopulmonary assessment and treatment practices
Methodological detailsweb-based survey, global, PRISMA-SCR framework
- Web-based survey
- Global
- PRISMA-SCR framework
Main finding
As reported in the abstract
- Significant variations in cardiopulmonary assessment practices across regions and income levels
- Oral corticosteroid and cyclophosphamide use varies significantly by country income level, higher in low- and middle-income nations
- North America: P < 0.001
- North America: P = 0.004
Observational data: associations, not effects.
Further findings
Scoping review: relevant articles for data extraction
- Relevant articles identified (36 to 156 per domain), from 31,825 records screened by 39 investigators
- 848
Original publication
Developing consensus outcome measures in juvenile systemic sclerosis: a global survey of pediatric rheumatologists and literature review. Pediatr Rheumatol Online J. Published 2 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →