Vasculitis & polymyalgia rheumatica
Pulmonary arterial wall thickness increased in Behçet’s disease patients with major organ involvement: Is it a sign of severity?
Authors' conclusion
We observed that PA wall thickness was significantly higher in BD with major organ involvement compared with patients with only mucocutaneous limited disease, HCs and NIPE.
Study context
- Population
- Patients with behçet's disease (BD), patients with non-inflammatory pulmonary embolism (NIPE) and healthy controls (HCs)
- Participants
- 77 / 33 / 57
- Exposure
- BD vs NIPE vs healthy controls
- BDn = 77
- NIPEn = 33
- HCsn = 57reference
- Outcome
- PA wall thickness by thickness by transthoracic echocardiography (TTE), measured at the mid-portion of the main PA
Methodological detailsechocardiographers blinded to cases
- Echocardiographers blinded to cases
Main finding
As reported in the abstract
PA wall thickness (TTE)
HCs vs NIPE: P < 0.001 · HCs vs BD: P < 0.001 · BD vs NIPE: P = 0.6
Observational data: associations, not effects.
Further findings
| Outcome | Values | P value |
|---|---|---|
| PA wall thickness in BD: major organ involvement vs mucocutaneous limited disease (subgroup)Major organ involvement vs mucocutaneous limited disease · significantly higher with major organ involvement | major organ involvement 4.7 (SD 0.4) mm · mucocutaneous limited disease 3.7 (SD 0.4) mm | P < 0.001 |
| PA wall thickness in BD: major organ involvement vs mucocutaneous limited disease (subgroup)Major organ involvement vs HCs | P < 0.001 | |
| PA wall thickness in BD: major organ involvement vs mucocutaneous limited disease (subgroup)Major organ involvement vs NIPE | P = 0.006 | |
| PA wall thickness in BD: vascular vs non-vascular major organ involvement (subgroup)Comparable | vascular 4.6 (SD 0.5) mm | P = 0.3 |
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Pulmonary arterial wall thickness increased in Behçet’s disease patients with major organ involvement: Is it a sign of severity? Rheumatology (Oxford). Published 9 August 2022. doi:10.
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