Vasculitis & polymyalgia rheumatica

Organ damage is a major determinant of work productivity impairment in Behçet’s syndrome: a post hoc analysis of the BS Overall Damage Index (BODI) validation study

Rheumatology (Oxford)Published Post hoc analysis of the BODI prospective validation study

Authors' conclusion

Disease activity and organ damage accrual remarkably affect work productivity in BS patients.

Study context

Population
Patients with Behçet's syndrome (BS)
Participants
148 patients
Primary endpoint
Prevalence, magnitude and determinants of work productivity impairment (WPAI:GH), focusing on organ damage (BODI)
Methodological detailsregression analysis
  • Regression analysis

Primary result

As reported in the abstract

Work productivity impairment
Unemployed
34.5%
Unemployment associated with age (OR)
1.035
Unemployment associated with BODI score (OR for a 1-unit increase)
1.313
Overall work impairment in employed patients
≈64.2%
Absenteeism (missing work hours due to health)
22.7%
Absenteeism, mean time loss
34.4%
Presenteeism (reduced performance at work due to health)
60.2%
Presenteeism, mean productivity impairment
45.4%
Absenteeism associated with ocular damage (β)
0.225
Presenteeism associated with female sex (β)
0.260
Presenteeism associated with PGA of disease activity (β)
0.502
Presenteeism associated with BODI score (β for 1-point increase)
0.166
Overall work impairment associated with FM (β)
0.246
Overall work impairment associated with PGA (β)
0.469
Overall work impairment associated with musculoskeletal damage (β)
0.325

Original publication

Organ damage is a major determinant of work productivity impairment in Behçet’s syndrome: a post hoc analysis of the BODI validation study. Rheumatology (Oxford). Published 13 December 2023. doi:10.1093/rheumatology/kead681

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