Vasculitis & polymyalgia rheumatica
Organ damage is a major determinant of work productivity impairment in Behçet’s syndrome: a post hoc analysis of the BS Overall Damage Index (BODI) validation study
Authors' conclusion
Disease activity and organ damage accrual remarkably affect work productivity in BS patients.
Study context
- Population
- Patients with Behçet's syndrome (BS)
- Participants
- 148 patients
- Primary endpoint
- Prevalence, magnitude and determinants of work productivity impairment (WPAI:GH), focusing on organ damage (BODI)
Methodological detailsregression analysis
- Regression analysis
Primary result
As reported in the abstract
Work productivity impairment
- Unemployed
- 34.5%
- Unemployment associated with age (OR)
- 1.035
- Unemployment associated with BODI score (OR for a 1-unit increase)
- 1.313
- Overall work impairment in employed patients
- ≈64.2%
- Absenteeism (missing work hours due to health)
- 22.7%
- Absenteeism, mean time loss
- 34.4%
- Presenteeism (reduced performance at work due to health)
- 60.2%
- Presenteeism, mean productivity impairment
- 45.4%
- Absenteeism associated with ocular damage (β)
- 0.225
- Presenteeism associated with female sex (β)
- 0.260
- Presenteeism associated with PGA of disease activity (β)
- 0.502
- Presenteeism associated with BODI score (β for 1-point increase)
- 0.166
- Overall work impairment associated with FM (β)
- 0.246
- Overall work impairment associated with PGA (β)
- 0.469
- Overall work impairment associated with musculoskeletal damage (β)
- 0.325
Original publication
Organ damage is a major determinant of work productivity impairment in Behçet’s syndrome: a post hoc analysis of the BODI validation study. Rheumatology (Oxford). Published 13 December 2023. doi:10. 1093/ rheumatology/ kead681
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