Lupus & antiphospholipid syndrome
Prevalence, sociodemographic characteristics and spatial distribution of systemic lupus erythematosus in France: a nationwide study using health claims data with insights into hydroxychloroquine prescription patterns
Authors' conclusion
Our study provides recent, accurate estimates of the prevalence and social and geographical distribution of SLE in France.
Study context
- Population
- Patients with SLE identified in the French national health data system (covering almost all 67 million people living in France), inpatients and people with long-term disease status, 2020patients with SLE identified
- Participants
- 54,804 patients
- Outcome
- Prevalence of SLE in France
- Follow-up
- 2020
Methodological detailsnationwide, health claims data
- Nationwide
- Health claims data
Main finding
As reported in the abstract
SLE prevalence
Overall prevalence
81.6 per 100 000 people
Prevalence in women
137.0 per 100 000
Prevalence in men
22.5 per 100 000
Observational data: associations, not effects.
Further findings
Spatial distribution of standardised prevalence
- Highest standardised prevalences in the French overseas departments and in the mainland departments to which people from these departments frequently migrate
Association with social deprivation index (mainland France)
- No association between SLE prevalence and a social deprivation index
HCQ prescription filled at least once
- Overall
- 67.7%
- Aged 20–24
- 86.7%
Original publication
Prevalence, sociodemographic characteristics and spatial distribution of systemic lupus erythematosus in France: a nationwide study using health claims data with insights into hydroxychloroquine prescription patterns. Lupus Sci Med. Published 22 July 2025. doi:10.
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