Prevalence and risk factors of falls in adults with rheumatoid arthritis: A systematic review and meta-analysis
Authors' conclusion
This meta-analysis provides a comprehensive evidence-based assessment of the prevalence and risk factors for falls in adults with RA, confirming their multifactorial etiology.
Study context
- Population
- Adults with rheumatoid arthritis (RA)
- Participants
- 24,123 adults34 studies
- Outcome
- Prevalence and risk factors of falls
Methodological detailsrandom-effects models, test for heterogeneity, Databases searched from inception to July 4, 2022 (PubMed, EMBASE, Web of Science, Cochrane Library, Cumulative Index to Nursing & Allied Health Literature (CINAHL), Wanfang, CNKI, VIP, CBM), Random-effects models with a test for heterogeneity; pooled incidence and odds ratios (ORs) for factors investigated in at least 2 studies; Stata 15.0
- Random-effects models
- Test for heterogeneity
- Databases searched from inception to July 4, 2022 (PubMed, EMBASE, Web of Science, Cochrane Library, CINAHL, Wanfang, CNKI, VIP, CBM)
- Random-effects models with a test for heterogeneity; pooled incidence and ORs for factors investigated in at least 2 studies; Stata 15.0
Pooled result
As reported in the abstract
Pooled prevalence of falls
- Any falls, pooled prevalence
- 34% (95% CI: 29% to 38%, I2=97.7%, P<0.001)
- Recurrent falls, pooled prevalence
- 16% (95% CI: 12% to 20%, I2=97.5%, P<0.001)
- History of falls, OR
- 3.08 (95%CI: 2.32 to 4.08, I2=0.0%, P = 0.660)
- History of fracture, OR
- 4.03 (95%CI: 3.12 to 5.21, I2=97.3%, P<0.001)
- Walking aid use, OR
- 1.60 (95%CI: 1.23 to 2.08, I2=67.7%, P = 0.026)
- Dizziness, OR
- 1.95 (95%CI: 1.43 to 2.64, I2=82.9%, P = 0.003)
- Psychotropic medication use, OR
- 1.79 (95%CI: 1.39 to 2.30, I2=22.0%, P = 0.254)
- Antihypertensive medicine/diuretic, OR
- 1.83 (95%CI: 1.37 to 2.46, I2=51.4%, P = 0.055)
- Taking four or more medicines, OR
- 1.51 (95%CI: 1.26 to 1.81, I2=26.0%, P = 0.256)
- HAQ score, OR
- 1.54 (95%CI: 1.40 to 1.69, I2=36.9%, P = 0.135)
Original publication
Prevalence and risk factors of falls in adults with rheumatoid arthritis: A systematic review and meta-analysis. Semin Arthritis Rheum. Published 10 March 2023. doi:10.
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