Survival of adults with rheumatoid arthritis associated interstitial lung disease - A systematic review and meta-analysis
Authors' conclusion
This review summarises the high mortality of RA-ILD, however the strength of conclusions that can be made is limited by the heterogeneity of the available studies, due to methodological and clinical factors.
Study context
- Population
- Adults with RA-ILD; survival from time of diagnosis78 studies
- Outcome
- Duration of survival from time of diagnosis of RA-ILD
Methodological detailsrisk of bias assessed with 4 domains of the Quality In Prognosis Studies tool
- Risk of bias assessed with 4 domains of the Quality In Prognosis Studies tool
Pooled result
As reported in the abstract
- Median survival (range across studies)
- 2 to 14 years
- Pooled cumulative mortality up to 1 year
- 9.0% (95% CI 6.1, 12.5, I2 88.9%)
- Pooled cumulative mortality >1 to ≤3 years
- 21.4% (17.3, 25.9, I2 85.7%)
- Pooled cumulative mortality >3 to ≤5 years
- 30.2% (24.8, 35.9, I2 87.7%)
- Pooled cumulative mortality >5 to ≤10 years
- 49.1% (40.6, 57.7 I2 85.0%)
Original publication
Survival of adults with rheumatoid arthritis associated interstitial lung disease - A systematic review and meta-analysis. Semin Arthritis Rheum. Published 9 March 2023. doi:10.
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