Pregnancy outcomes in women with idiopathic inflammatory myopathies: a single-centre study from Sweden
Authors' conclusion
Women with IIM, both before and after diagnosis, had higher proportions of labour induction, caesarean delivery, and instrumental delivery than the general population, regardless of low IIM disease activity at time of pregnancy.
Study context
- Population
- Women with IIM aged 18–40 years diagnosed at Karolinska University Hospital and included in SweMyoNet 2006–2022
- Participants
- 34 births
- Exposure
- Births in women with IIM vs the Swedish general obstetric population
- Pre-IIMn = 10
- Post-IIMn = 24
- Outcome
- Pregnancy and delivery outcomes
Methodological detailssingle-centre, comparison with Swedish general obstetric population
- Single-centre
- Comparison with Swedish general obstetric population
Main finding
As reported in the abstract
Caesarean delivery: all IIM births vs general obstetric population
29% vs 21%
Labour induction: all IIM births vs general obstetric population
27% vs 18%
Instrumental delivery: all IIM births vs general obstetric population
21% vs 9.1%
Preterm births: all IIM births vs general obstetric population
3.0% vs 5.6%
Observational data: associations, not effects.
Further findings
IIM disease activity at time of pregnancy
- Overall low according to Manual Muscle Test-8, creatinine kinase and GC doses
Original publication
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