Lupus & antiphospholipid syndrome
Predictors of Organ Damage in Systemic Lupus Erythematosus in the Asia Pacific Region: A Systematic Review
Authors' conclusion
Predictors of organ damage in SLE in Asia Pacific are similar to other regions.
Study context
- Population
- Adult patients with systemic lupus erythematosus (SLE) in the Asia Pacific region38 studies
- Outcome
- Predictors of organ damage (SLICC/ACR DI)
Methodological detailstwo independent reviewers, risk of bias assessed with Newcastle-Ottawa Scale and Joanna Briggs Institute tool, Medline, PubMed, Embase and Web of Science searched August 31 to September 5, 2022; studies from 1999 to 2022
- Two independent reviewers
- Risk of bias assessed with Newcastle-Ottawa Scale and Joanna Briggs Institute tool
- Medline, PubMed, Embase and Web of Science searched August 31 to September 5, 2022; studies from 1999 to 2022
Pooled result
As reported in the abstract
Predictors of organ damage
- Older age, GC use, longer disease duration and disease activity predictive of organ damage
- LN a risk factor for renal and overall damage accrual
- HCQ protective against overall organ damage
Further pooled results
- Studies reporting organ damage at study enrollment
- 22 (58%)
- Studies reporting damage accrual
- 19 (50%)
Original publication
Predictors of Organ Damage in Systemic Lupus Erythematosus in the Asia Pacific Region: A Systematic Review. Arthritis Care Res (Hoboken). Published 22 February 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →