Lupus & antiphospholipid syndrome
Declining Incidence of Systemic Lupus Erythematosus in Norway 1999–2017: Data From a Population Cohort Identified by International Classification of Diseases, 10th Revision Code and Verified by Classification
Authors' conclusion
In a presumably complete population-based cohort, we identified decreasing incidence of SLE, especially among female persons 50 to 59 years old.
Study context
- Population
- All cases ICD-10 coded as systemic lupus erythematosus (SLE) in Southeast Norway (2.9 million inhabitants), 1999 through 2017797 new-onset SLE
- Participants
- 3,488 participants
- Outcome
- Annual incidence rates of classified SLE, and subsets by age at diagnosis, sex and parental country of birth
Methodological detailsICD-10 coded cases verified by chart review and classification criteria, chi-square test for linear time trend
- ICD-10 coded cases verified by chart review and classification criteria
- Chi-square test for linear time trend
Main finding
As reported in the abstract
Annual SLE incidence, 1999 to 2017
- Incidence in females 50 to 59 years old at diagnosis fell from 3.4 to 1.1 per 100,000 persons
- P trend < 0.001
Observational data: associations, not effects.
Further findings
Chart-confirmed SLE among ICD-10 coded cases
- Confirmed SLE diagnosis
- 1,558 (45%)
Accuracy of ICD-10 codes for incident SLE diagnosis
- Acceptable in juveniles and young adults (up to 20 years) but otherwise low
Prescriptions of menopausal hormone treatment (ecological data)
- Reduction
- 74%
Original publication
Declining Incidence of Systemic Lupus Erythematosus in Norway 1999–2017: Data From a Population Cohort Identified by International Classification of Diseases, 10th Revision Code and Verified by Classification. Arthritis Rheumatol. Published 21 February 2024. doi:10.
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