Systemic sclerosis & Raynaud's

Prediction of damage trajectories in systemic sclerosis using group-based trajectory modelling

Rheumatology (Oxford)Published Prognostic model development and validation study

Authors' conclusion

A simple model using only cutaneous subset, baseline DI and sex can predict damage accumulation in early SSc.

Study context

Population
SSc patients with <2 years disease duration; derivation cohort from Canada and Australia, validation cohort from the Netherlands
Comparison
lcSSc vs dcSSc
Outcome
Prediction of inclusion in 'good' or 'bad' damage (Damage Index (DI)) trajectories
Methodological detailsgroup-based trajectory modelling, derivation and validation cohorts
  • Group-based trajectory modelling
  • Derivation and validation cohorts

Performance

As reported in the abstract

Test or modelROC AUC
lcSSc0.9313
dcSSc0.9027

ROC AUC

lcSSc0.9313
dcSSc0.9027

Original publication

Prediction of damage trajectories in systemic sclerosis using group-based trajectory modelling. Rheumatology (Oxford). Published 10 January 2023. doi:10.1093/rheumatology/kead002

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