Systemic sclerosis & Raynaud's

Patient and Physician Global Assessments of Disease Status in Systemic Sclerosis

Arthritis Care Res (Hoboken)Published Literature review

Authors' conclusion

Marked heterogeneity was found in the wording and measurement scales of the global assessments applied in RCTs. These instruments were not developed using rigorous methodology and have not been fully validated.

Study context

Population
Randomized Controlled Trials (RCTs) of SSc using PtGA and PhGA
Outcome
Formats, wording and clinimetric properties of PtGA and PhGA in SSc RCTs
Methodological detailscomprehensive
  • Comprehensive

Main finding

As reported in the abstract

  • Marked heterogeneity in the wording and measurement scales of the global assessments applied in RCTs
  • Instruments not developed using rigorous methodology and not fully validated

Original publication

Patient and Physician Global Assessments of Disease Status in Systemic Sclerosis. Arthritis Care Res (Hoboken). Published 6 January 2023. doi:10.1002/acr.25056

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