Systemic sclerosis & Raynaud's
Association of Race and Risk of Future Scleroderma Renal Crisis at Systemic Sclerosis Diagnosis
Main finding · SRCResult — go to the resultOdds ratio 6.4 95% CI 1.3–31.2Authors' conclusion
Black race was independently associated with a higher risk of future SRC.
Study context
- Population
- Patients with Systemic Sclerosis (SSc) in the US Military Health System, 2005–201631 scleroderma renal crisis (SRC) cases · 322 controls
- Participants
- 353 patients
- Comparison
- Black vs non-Black race
- Blackn = 79
- Non-Blackn = 215reference
- Outcome
- Future development of scleroderma renal crisis (SRC)
Methodological detailsnested in SSc cohort, logistic regression adjusted for age, eGFR, hypertension and proteinuria at SSc diagnosis
- Nested in SSc cohort
- Logistic regression adjusted for age, eGFR, hypertension and proteinuria at SSc diagnosis
Main finding
SRC
Odds ratio
6.4
95% CI 1.3–31.2
P = 0.02
Events by group
Blackvs Non-Black
OR 6.4 (95% CI 1.3–31.2); P = 0.02
As reported in the abstract
Observational data: associations, not effects.
Further findings
Anti-Ro antibody in Black patients, SRC vs without SRC
P = 0.01
Predictors of SRC in non-Black cohort
- Older age, thrombocytopenia and anti-RNA polymerase III antibody at SSc diagnosis significantly associated with future SRC
Original publication
Association of Race and Risk of Future Scleroderma Renal Crisis at Systemic Sclerosis Diagnosis. Arthritis Care Res (Hoboken). Published 20 December 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →