Lupus & antiphospholipid syndrome
Predicting anxiety and depression in systemic lupus erythematosus: the role of inflammation, sociodemographic variables and clinical factors
Authors' conclusion
The findings of this exploratory study provide potential models predicting depression and anxiety symptoms in SLE.
Study context
- Population
- Patients with systemic lupus erythematosus (SLE) enrolled in a longitudinal study of cognition in SLE
- Participants
- 238 patients
- Outcome
- Depression (Beck Depression Inventory-II) and anxiety (Beck Anxiety Inventory) scores, and clinically significant depression and anxiety symptoms (cut-off scores validated in SLE)
- Follow-up
- Baseline
Methodological detailsbaseline data from a longitudinal study of cognition in SLE, random forests, exploratory
- Baseline data from a longitudinal study of cognition in SLE
- Random forests
- Exploratory
Main finding
As reported in the abstract
Discrimination of clinically significant depression/anxiety by multivariate models (sociodemographic, clinical, analytes)
AUC, depression
0.85
AUC, anxiety
0.77
AUC, both depression and anxiety
0.82
Observational data: associations, not effects.
Original publication
Predicting anxiety and depression in systemic lupus erythematosus: the role of inflammation, sociodemographic variables and clinical factors. Semin Arthritis Rheum. Published 9 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →