Lupus & antiphospholipid syndrome
Positive psychosocial factors may protect against perceived stress in people with systemic lupus erythematosus with and without trauma history
Authors' conclusion
Enhancing positive and lessening negative psychosocial factors may mitigate deleterious perceived stress, which may improve outcomes in SLE, even among individuals with a history of prior trauma who may be more vulnerable to recent stressful events.
Study context
- Population
- Adults with SLE in the California Lupus Epidemiology Study
- Participants
- 242 adults
- Outcome
- Perceived stress: associations with recent stressful events and positive and negative psychosocial factors
Methodological detailscross-sectional analysis of the California Lupus Epidemiology Study cohort, multivariable linear regression, stratified by lifetime trauma history (Brief Trauma Questionnaire (BTQ)) and adverse childhood experiences (ACEs)
- Cross-sectional analysis of the California Lupus Epidemiology Study cohort
- Multivariable linear regression
- Stratified by lifetime trauma history (BTQ) and ACEs
Main finding
As reported in the abstract
Greater number of recent stressful events, beta
0.20 (0.07 to 0.33), p=0.003 (95% CI)
Positive psychosocial factor score (resilience, self-efficacy, emotional support), accounting for stressful events, beta
−0.67 (−0.94 to −0.40), p<0.0001 (95% CI)
Social isolation, beta
0.20 (0.14 to 0.25), p<0.0001 (95% CI)
Observational data: associations, not effects.
Further findings
Perceived stress, stratified by BTQ trauma and ACEs (subgroups)
- Recent stressful events, people with BTQ trauma, beta
- 0.17 (0.05 to 0.29), p=0.0077 (95% CI)
- Recent stressful events, people with ACEs, beta
- 0.37 (0.15 to 0.58), p=0.0011 (95% CI)
- Associations of psychosocial factors and perceived stress similar between groups
- Stressful events significantly associated with perceived stress only in those with BTQ trauma and ACEs
Original publication
Composed by AI from the published abstract and checked against it. How Briefs are made →