Sjögren's disease & overlap diseases
Population-based prevalence and incidence estimates of mixed connective tissue disease from the Manhattan Lupus Surveillance Program
Authors' conclusion
The MLSP provided estimates for the prevalence and incidence of MCTD in a diverse population.
Study context
- Population
- Manhattan Lupus Surveillance Program, a racially/ethnically diverse population-based registry of cases with SLE and related diseases including MCTD7.7% of cases met an MCTD definition
- Participants
- 258 participants
- Exposure
- Three case definitions of MCTD
- Outcome
- Prevalence and incidence of MCTD
Methodological detailsracially/ethnically diverse
- Racially/ethnically diverse
Main finding
As reported in the abstract
| Group | Value | Age-adjusted prevalence | Age-adjusted incidence (95% CI 0.22, 0.64) | Age-adjusted incidence (95% CI 1.49, 2.39) |
|---|---|---|---|---|
| Modified Alarcon-Segovia and Kahn criteria | 1.28 (95% CI 0.72–2.09) per 100 000 | 1.28 | ||
| MCTD diagnosis, no other CTD | 2.98 (95% CI 2.10–4.11) per 100 000 | 2.98 | 0.39 | |
| MCTD diagnosis regardless of other CTD | 16.22 (95% CI 14.00–18.43) per 100 000 | 16.22 | 1.90 |
Value
Modified Alarcon-Segovia and Kahn criteria1.28 (95% CI 0.72–2.09) per 100 000
MCTD diagnosis, no other CTD2.98 (95% CI 2.10–4.11) per 100 000
MCTD diagnosis regardless of other CTD16.22 (95% CI 14.00–18.43) per 100 000
Age-adjusted prevalence
Modified Alarcon-Segovia and Kahn criteria1.28
MCTD diagnosis, no other CTD2.98
MCTD diagnosis regardless of other CTD16.22
Age-adjusted incidence (95% CI 0.22, 0.64)
Modified Alarcon-Segovia and Kahn criteria— not stated in the abstract
MCTD diagnosis, no other CTD0.39
MCTD diagnosis regardless of other CTD— not stated in the abstract
Age-adjusted incidence (95% CI 1.49, 2.39)
Modified Alarcon-Segovia and Kahn criteria— not stated in the abstract
MCTD diagnosis, no other CTD— not stated in the abstract
MCTD diagnosis regardless of other CTD1.90
Observational data: associations, not effects.
Original publication
Population-based prevalence and incidence estimates of mixed connective tissue disease from the Manhattan Lupus Surveillance Program. Rheumatology (Oxford). Published 20 December 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →