Sjögren's disease & overlap diseases

Pleural Irregularities: A new ultrasound marker for lung involvement in primary Sjögren's disease

Joint Bone SpinePublished Diagnostic accuracy study

Authors' conclusion

PI may represent a valid tool for the assessment of lung involvement in SjD, particularly for the screening of ILD.

Study context

Population
Primary Sjögren's disease (SjD) patients who had undergone chest CT in the last 2 months
Comparison
Lung ultrasound (LUS) pleural irregularity (pleural irregularities (PI)) total and postero-inferior scores vs chest CT for SjD-related lung involvement
  • Established interstitial lung disease (ILD)n = 19
  • Newly diagnosed ILDn = 4
Outcome
Role of LUS PI scores for assessment of SjD-related lung involvement (ILD diagnosis)

Performance

As reported in the abstract

SjD-ILD diagnosis
Test or modelSensitivitySpecificity
PI postero-inferior score (cut-off 15)86.6%84.2%

PI postero-inferior score (cut-off 15)

Sensitivity86.6%
Specificity84.2%

Further findings

R

OutcomePI total scorePI postero-inferior score
Correlation of PI scores with HRCT Warrick score0.8090.854

Correlation with PFT

Correlation between PFT and PI scores higher than between PFT and Warrick HRCT score

Original publication

Pleural Irregularities: A new ultrasound marker for lung involvement in primary Sjögren's disease. Joint Bone Spine. Published 17 November 2024. doi:10.1016/j.jbspin.2024.105820

Composed by AI from the published abstract and checked against it. How Briefs are made →

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