Sjögren's disease & overlap diseases
Pleural Irregularities: A new ultrasound marker for lung involvement in primary Sjögren's disease
Authors' conclusion
PI may represent a valid tool for the assessment of lung involvement in SjD, particularly for the screening of ILD.
Study context
- Population
- Primary Sjögren's disease (SjD) patients who had undergone chest CT in the last 2 months
- Comparison
- Lung ultrasound (LUS) pleural irregularity (pleural irregularities (PI)) total and postero-inferior scores vs chest CT for SjD-related lung involvement
- Established interstitial lung disease (ILD)n = 19
- Newly diagnosed ILDn = 4
- Outcome
- Role of LUS PI scores for assessment of SjD-related lung involvement (ILD diagnosis)
Performance
As reported in the abstract
SjD-ILD diagnosis
| Test or model | Sensitivity | Specificity |
|---|---|---|
| PI postero-inferior score (cut-off 15) | 86.6% | 84.2% |
PI postero-inferior score (cut-off 15)
Sensitivity86.6%
Specificity84.2%
Further findings
R
| Outcome | PI total score | PI postero-inferior score |
|---|---|---|
| Correlation of PI scores with HRCT Warrick score | 0.809 | 0.854 |
Correlation with PFT
- Correlation between PFT and PI scores higher than between PFT and Warrick HRCT score
Original publication
Pleural Irregularities: A new ultrasound marker for lung involvement in primary Sjögren's disease. Joint Bone Spine. Published 17 November 2024. doi:10. 1016/ j. jbspin. 2024. 105820
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