Lupus & antiphospholipid syndrome

Physical Performance in a Diverse, Population‐Based Cohort of Individuals With Systemic Lupus Erythematosus

Arthritis Care Res (Hoboken)Published Cross-sectional study

Authors' conclusion

In our population-based, primarily Black cohort, we found that individuals with SLE commonly had poor physical performance.

Study context

Population
Individuals with systemic lupus erythematosus (SLE) from a population-based metropolitan Atlanta cohort (primarily Black)
Participants
446 individuals
Exposure
Intermediate-low vs high physical performance
Outcome
Physical performance via the Short Physical Performance Battery (score 0-12); intermediate-low (<10) vs high (≥10)
Methodological detailssingle-visit, population-based, multivariable logistic regression
  • Single-visit
  • Population-based
  • Multivariable logistic regression

Main finding

As reported in the abstract

Intermediate-low physical performance (prevalence)

Participants with intermediate-low overall physical performance

59.6%

Observational data: associations, not effects.

Further findings

Correlates of intermediate-low vs high physical performance

aOR (95% CI)
Current employment0.69 (0.45–1.05)
Higher cognitive functioning0.57 (0.42–0.77)
Higher BMI1.25 (1.01–1.56)
Disease activity1.59 (1.27–1.98)
Disease burden1.38 (1.08–1.77)

Maximum score on SPPB component tasks

Maximum score, lower body strength task
7%
Maximum score, balance task
90%
Maximum score, gait speed task
76%

Correlates of intermediate-low vs high physical performance

Higher depressive symptoms, perceived stress scores and lower educational attainment associated with poorer performance (not statistically significant)

Original publication

Physical Performance in a Diverse, Population‐Based Cohort of Individuals With Systemic Lupus Erythematosus. Arthritis Care Res (Hoboken). Published 16 January 2024. doi:10.1002/acr.25266

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