Physical Activity and Features of Knee Osteoarthritis on Magnetic Resonance Imaging in Individuals Without Osteoarthritis: A Systematic Review
Authors' conclusion
Within the sparse and diverse evidence available, no strong evidence was found for the presence or absence of an association between PA and the presence or progression of features of OA on MRI among subjects without OA.
Study context
- Population
- Subjects without osteoarthritis (OA), average age 35–80 years2 RCTs · 16 observational studies
- Comparison
- Physical activity (PA) levels and features of knee OA on magnetic resonance imaging (MRI)
- Outcome
- OA-related MRI measures of intraarticular knee joint structures
Methodological detailsprospective studies
- Prospective studies
Pooled result
As reported in the abstract
- Cartilage volume or thickness: PA harmfully related in 1 of 11 studies; significant protective association in 4 studies
- Cartilage defects: PA harmfully related in 4 of 10 studies; others no significant associations
- Cartilage T2 value: significantly increased with more PA in 2 of 3 studies
- Bone marrow lesions: no significant association with PA in all 3 studies
- Meniscus pathology (2 studies): only occupational PA involving knee bending associated with greater risk of progression
Original publication
Physical Activity and Features of Knee Osteoarthritis on Magnetic Resonance Imaging in Individuals Without Osteoarthritis: A Systematic Review. Arthritis Care Res (Hoboken). Published 21 February 2023. doi:10.
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