Osteoarthritis

Diagnostic Accuracy of Ultrasound for Assessment of Synovial Abnormalities Among Patients With Knee Pain: A Meta‐Analysis

Arthritis Care Res (Hoboken)Published Systematic review and meta-analysis of diagnostic accuracy studies

Authors' conclusion

Ultrasound demonstrated a promising accuracy in detecting synovial abnormalities among patients with knee pain.

Study context

Population
Patients with knee pain
Participants
755 patients14 studies
Comparison
US vs magnetic resonance imaging (MRI) for synovial abnormalities
Outcome
Diagnostic accuracy of US vs MRI for synovial abnormalities (synovitis and synovial effusion)
Methodological detailsbivariate model, random effects model
  • Bivariate model
  • Random effects model

Pooled result

As reported in the abstract

Synovitis, diagnostic accuracy of US vs MRI
GroupPooled sensitivityPooled specificityAUC
US0.88 (95% CI 0.65-0.96)0.70 (95% CI 0.51-0.84)0.81 (95% CI 0.77-0.84)

US

Pooled sensitivity0.88 (95% CI 0.65-0.96)
Pooled specificity0.70 (95% CI 0.51-0.84)
AUC0.81 (95% CI 0.77-0.84)

Further pooled results

OutcomeUSR (95% CI)
Synovial effusion, diagnostic accuracy of US vs MRI
Pooled sensitivity0.90 (95% CI 0.81-0.95)
Pooled specificity0.86 (95% CI 0.77-0.92)
AUC0.94 (95% CI 0.91-0.96)
Correlation of US- and MRI-diagnosed synovitisStrong correlation0.64 (0.56–0.71)
Correlation of US- and MRI-diagnosed synovial effusionStrong correlation0.63 (0.52–0.73)

Original publication

Diagnostic Accuracy of Ultrasound for Assessment of Synovial Abnormalities Among Patients With Knee Pain: A Meta‐Analysis. Arthritis Care Res (Hoboken). Published 25 October 2023. doi:10.1002/acr.25205

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