Does Physical Activity Confound Race Differences in Osteoarthritis‐Related Functional Limitation?
Authors' conclusion
Greater physical activity is unlikely to completely make up for race differences in OA-related functional limitation
Study context
- Population
- Osteoarthritis (OA) Initiative participants with or at increased risk of knee OA who wore an accelerometer
- Participants
- 226 vs 1,348
- Exposure
- African American vs White participants, unadjusted and adjusted for moderate to vigorous physical activity
- African American (AA)n = 226
- Whiten = 1,348reference
- Outcome
- Incident OA-related functional limitation: inability to achieve community walking speed (1.2 m/s), slow walking speed (<1.0 m/s), low physical functioning (WOMAC physical function >28 of 68)
Methodological detailsaccelerometer-measured physical activity
- Accelerometer-measured physical activity
Main finding
As reported in the abstract
Inability to walk a community walking speed
AA vs WhiteRelative risk (95% CI)
Unadjusted
2.15(1.64–2.81)
Adjusted for time in moderate to vigorous physical activity
1.99(1.51–2.61)
Observational data: associations, not effects.
Further findings
| Outcome | RR (95% CI) | |
|---|---|---|
| Slow walking speedAAvs WhiteUnadjusted | 2.06 (1.40–3.01) | |
| Slow walking speedAAvs WhiteAdjusted for time in moderate to vigorous physical activity | 1.82 (1.25–2.63) | |
| Low physical functioning (WOMAC)AAvs WhiteUnadjusted | 3.44 (1.96–6.03) | |
| Low physical functioning (WOMAC)AAvs WhiteAdjusted for time in moderate to vigorous physical activity | 3.10 (1.79–5.39) | |
| 0.10.31310Relative risk (log scale) |
Low physical functioning (WOMAC)
- When further adjusted for demographic and other clinical variables, association significantly decreased and no longer met statistical significance
Original publication
Does Physical Activity Confound Race Differences in Osteoarthritis‐Related Functional Limitation? Arthritis Care Res (Hoboken). Published 25 October 2023. doi:10.
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