Radiographic joint space width in individuals with hand osteoarthritis: Are their “healthy” joints really healthy?
Authors' conclusion
Unaffected finger joints in people with IPOA had narrower joint space than joints of healthy controls.
Study context
- Population
- Osteoarthritis Initiative participants with available dominant hand radiographs at baseline
- Participants
- 3,394 participants
- Exposure
- Interphalangeal OA (IPOA) cases vs controls without IPOA
- Outcome
- Radiographic JSW of MCP, PIP and DIP joints (fingers 2-5) without radiographic osteoarthritis (OA) (KL score=0)
- Follow-up
- Baseline
Methodological detailsgeneralized estimating equation models, adjusted for age, gender, metacarpal length, and joint type
- Generalized estimating equation models
- Adjusted for age, gender, metacarpal length, and joint type
Main finding
As reported in the abstract
JSW in finger joints without radiographic OA
- Significantly narrower joint space width (JSW) in the IPOA group vs controls
- IPOA vs Controls: P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | P value |
|---|---|
| JSW by joint type and sub-region (total, central, lateral) | P < 0.001 |
- JSW by joint type and sub-region (total, central, lateral): differences significant across all joint types and sub-regions
JSW by joint type and sub-region (total, central, lateral)
- Differences significant across all joint types, for total JSW and central and lateral sub-regions
Original publication
Radiographic joint space width in individuals with hand osteoarthritis: Are their “healthy” joints really healthy? Osteoarthritis Cartilage. Published 20 October 2023. doi:10. 1016/ j. joca. 2023. 10. 004
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