Osteoarthritis

Radiographic joint space width in individuals with hand osteoarthritis: Are their “healthy” joints really healthy?

Osteoarthritis CartilagePublished Cross-sectional study

Authors' conclusion

Unaffected finger joints in people with IPOA had narrower joint space than joints of healthy controls.

Study context

Population
Osteoarthritis Initiative participants with available dominant hand radiographs at baseline
Participants
3,394 participants
Exposure
Interphalangeal OA (IPOA) cases vs controls without IPOA
Outcome
Radiographic JSW of MCP, PIP and DIP joints (fingers 2-5) without radiographic osteoarthritis (OA) (KL score=0)
Follow-up
Baseline
Methodological detailsgeneralized estimating equation models, adjusted for age, gender, metacarpal length, and joint type
  • Generalized estimating equation models
  • Adjusted for age, gender, metacarpal length, and joint type

Main finding

As reported in the abstract

JSW in finger joints without radiographic OA
  • Significantly narrower joint space width (JSW) in the IPOA group vs controls
  • IPOA vs Controls: P < 0.001

Observational data: associations, not effects.

Further findings

OutcomeP value
JSW by joint type and sub-region (total, central, lateral)P < 0.001
  • JSW by joint type and sub-region (total, central, lateral): differences significant across all joint types and sub-regions

JSW by joint type and sub-region (total, central, lateral)

Differences significant across all joint types, for total JSW and central and lateral sub-regions

Original publication

Radiographic joint space width in individuals with hand osteoarthritis: Are their “healthy” joints really healthy? Osteoarthritis Cartilage. Published 20 October 2023. doi:10.1016/j.joca.2023.10.004

Composed by AI from the published abstract and checked against it. How Briefs are made →

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