Spondyloarthritis & psoriatic arthritis
Patients’ Perspectives on Axial Pain in Relation to Inflammation and Structural Damage in a Large Cohort of Axial Spondyloarthritis Patients
Authors' conclusion
In our large observational cohort, the majority of patients with axSpA could not differentiate the origin of experienced axial pain.
Study context
- Population
- Patients with axial spondyloarthritis (axSpA) from the Groningen Leeuwarden Axial Spondyloarthritis (GLAS) cohort visiting the outpatient clinic, 2016–2019 (24% nr-axSpA; 62% male; mean age 48 years)24% nr-axSpA
- Participants
- 688 patients
- Exposure
- Patients linking axial pain predominantly to inflammation vs predominantly to damage vs unable to link
- Outcome
- Extent to which patients link neck, back and hip pain to inflammation and/or structural damage (two NRS 0–10 questions; ≥2-point difference clinically relevant)
Methodological detailsobservational cohort (GLAS)
- Observational cohort (GLAS)
Main finding
As reported in the abstract
Attributed origin of axial pain
Observational data: associations, not effects.
Further findings
Characteristics of the inflammation group
- Inflammation group younger, shorter symptom duration, more often nr-axSpA, higher ASDAS-CRP, more often elevated CRP, fewer comorbidities, better spinal mobility and less spinal radiographic damage
Original publication
Patients’ Perspectives on Axial Pain in Relation to Inflammation and Structural Damage in a Large Cohort of Axial Spondyloarthritis Patients. Arthritis Care Res (Hoboken). Published 5 January 2024. doi:10.
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