Spondyloarthritis & psoriatic arthritis
Topography of entheseal lesions on ultrasound: a comparative study between axial spondyloarthritis, psoriatic arthritis and healthy controls
Authors' conclusion
To distinguish SpA patients from controls, the sonographic scoring system used should account not only for the presence of specific entheseal lesions (structural and inflammatory) but also for the individual site affected.
Study context
- Population
- Patients with PsA and axial SpA (axSpA) from six Swiss hospital outpatient clinics, and healthy controls (HC); US of nine entheseal sites bilaterally scored by OMERACT criteria2,178 entheses evaluated
- Participants
- 121 patients
- Exposure
- Spondyloarthritis (SpA) vs HC
- PsAn = 41
- axSpAn = 39
- HCn = 41reference
- Outcome
- Anatomical sites and US entheseal lesions best discriminating SpA from HC
Methodological detailscomparative, multicentre (six Swiss hospital outpatient clinics), univariable and multivariable analyses
- Comparative
- Multicentre (six Swiss hospital outpatient clinics)
- Univariable and multivariable analyses
Main finding
As reported in the abstract
Odds ratio
1.38
P = 0.034
B-mode inflammatory lesions
Odds ratio
4.45
P = 0.030
active enthesitis
Odds ratio
1.74
P = 0.039
distal patellar ligament insertion
Observational data: associations, not effects.
Further findings
Inflammatory markers and disease activity scores, PsA vs axSpA
- No significant differences between PsA and axSpA
Original publication
Topography of entheseal lesions on ultrasound: a comparative study between axial spondyloarthritis, psoriatic arthritis and healthy controls. RMD Open. Published 15 October 2025. doi:10.
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