Occupational therapist-led versus rheumatologist-led care in people with hand osteoarthritis in Norway: an open-label, multicentre, randomised controlled, non-inferiority trial
Primary result · OMERACT-OARSI respondersResult — go to the resultOdds ratio 1.01 95% CI 0.63–1.62Authors' conclusion
Occupational therapist-led care for hand osteoarthritis is non-inferior to rheumatologist-led care in terms of efficacy and safety.
Study context
- Population
- Participants with hand OA aged 18 years or older, two hospitals in Norway302 (80.7%) women
- Participants
- 374 participants
- Comparison
- Occupational therapist-led care vs rheumatologist-led care
- Occupational therapist-led caren = 188
- Rheumatologist-led caren = 186reference
- Primary endpoint
- Response to treatment according to the OMERACT-OARSI criteria
- Follow-up
- 6 months
Methodological detailsopen-label, multicentre, non-inferiority, stratified by centre
- Open-label
- Multicentre
- Non-inferiority
- Stratified by centre
Primary result
OMERACT-OARSI responders
Odds ratio
1.01
95% CI 0.63–1.62
Events by treatment group
Occupational therapist-led carevs Rheumatologist-led care
OR 1.01 (95% CI 0.63–1.62)
As reported in the abstract
Further findings
Cost-utility analysis (Norwegian health-care system perspective)
- Occupational therapist-led care cost-effective up to a willingness to pay per quality-adjusted life-year of
- £23 255
Safety
- No severe adverse events were recorded
Original publication
Occupational therapist-led versus rheumatologist-led care in people with hand osteoarthritis in Norway: an open-label, multicentre, randomised controlled, non-inferiority trial. Lancet Rheumatol. Published 10 June 2025. doi:10. 1016/ s2665-9913(25)00040-2
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