Vasculitis & polymyalgia rheumatica

Nailfold videocapillaroscopy in antineutrophil cytoplasmic antibody–associated vasculitis

Arthritis Res TherPublished Cross-sectional study

Authors' conclusion

There was no evidence of differences in nailfold capillaroscopy abnormalities between those diagnosed with AAV and the control group.

Study context

Population
Patients with a current diagnosis of AAV (median age 59; 52% women; GPA 58%, EGPA 21%, MPA 21%; 82% antineutrophil cytoplasmic antibody (ANCA) positive) and controls
Participants
33 vs 21
Exposure
AAV vs controls
  • AAVn = 33
  • Controlsn = 21reference
Outcome
Nailfold videocapillaroscopy abnormalities: capillary density, morphology, dilation, microhemorrhage and disorganization
Methodological detailscontrolled, semiquantitative analysis reviewed by 2 rheumatologists
  • Controlled
  • Semiquantitative analysis reviewed by 2 rheumatologists

Main finding

As reported in the abstract

Capillary density, dilation, morphology, microhemorrhages and disorganization
  • No statistically significant differences between the 2 groups

Observational data: associations, not effects.

Original publication

Nailfold videocapillaroscopy in antineutrophil cytoplasmic antibody–associated vasculitis. Arthritis Res Ther. Published 2 January 2024. doi:10.1186/s13075-023-03227-z

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