Pediatric rheumatology

Mortality and associated factors of JIA in hospitalized Thai children: a nationwide data analysis 2015–2023

Rheumatology (Oxford)Published Retrospective cohort study

Authors' conclusion

Although overall mortality and intubation rates were low, respiratory failure identified a small, high-risk subgroup with substantial mortality and healthcare burden.

Study context

Population
Hospital admissions of patients younger than 18 years with JIA, Thailand's National database, January 2015 to December 2023
Participants
3,754 JIA admissions
Outcome
In-hospital mortality and respiratory failure (defined by endotracheal intubation)
Methodological detailsnationwide administrative inpatient database, multivariable logistic regression
  • Nationwide administrative inpatient database
  • Multivariable logistic regression

Main finding

As reported in the abstract

Endotracheal intubation

39 admissions

1.0%

In-hospital deaths

17

In-hospital mortality rate

0.5%

Mortality among intubated patients

33.3%

Observational data: associations, not effects.

Further findings

Comorbidities associated with intubation

Myocarditis (strongest association), aOR
294.74
Followed by pulmonary haemorrhage, acute kidney injury and septic shock

Macrophage activation syndrome

Admissions with macrophage activation syndrome
43 (1.2%)
More frequent among non-survivors vs survivors
23.5% vs 1.0%; P < 0.001

LOS and costs

Substantially higher among intubated patients and non-survivors

Original publication

Mortality and associated factors of JIA in hospitalized Thai children: a nationwide data analysis 2015–2023. Rheumatology (Oxford). Published 20 August 2026. doi:10.1093/rheumatology/keag453

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