Mortality and associated factors of JIA in hospitalized Thai children: a nationwide data analysis 2015–2023
Authors' conclusion
Although overall mortality and intubation rates were low, respiratory failure identified a small, high-risk subgroup with substantial mortality and healthcare burden.
Study context
- Population
- Hospital admissions of patients younger than 18 years with JIA, Thailand's National database, January 2015 to December 2023
- Participants
- 3,754 JIA admissions
- Outcome
- In-hospital mortality and respiratory failure (defined by endotracheal intubation)
Methodological detailsnationwide administrative inpatient database, multivariable logistic regression
- Nationwide administrative inpatient database
- Multivariable logistic regression
Main finding
As reported in the abstract
Endotracheal intubation
39 admissions
1.0%
In-hospital deaths
17
In-hospital mortality rate
0.5%
Mortality among intubated patients
33.3%
Observational data: associations, not effects.
Further findings
Comorbidities associated with intubation
- Myocarditis (strongest association), aOR
- 294.74
- Followed by pulmonary haemorrhage, acute kidney injury and septic shock
Macrophage activation syndrome
- Admissions with macrophage activation syndrome
- 43 (1.2%)
- More frequent among non-survivors vs survivors
- 23.5% vs 1.0%; P < 0.001
LOS and costs
- Substantially higher among intubated patients and non-survivors
Original publication
Mortality and associated factors of JIA in hospitalized Thai children: a nationwide data analysis 2015–2023. Rheumatology (Oxford). Published 20 August 2026. doi:10. 1093/ rheumatology/ keag453
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