Disability and disease-related damage in Thai children and adolescents with juvenile idiopathic arthritis
Authors' conclusion
Disability and disease-related damage was identified in one-fifth and one-third of JIA patients.
Study context
- Population
- Children and adolescents with juvenile idiopathic arthritis (JIA) in a resource-restricted setting in Thailand, enrolled June 2019-June 202150.5% female
- Participants
- 101 children
- Outcome
- Prevalence of disability (Child Health Assessment Questionnaire (CHAQ), Steinbrocker classification) and damage (Juvenile Arthritis Damage Index (JADI), modified-JADI (mJADI))
Methodological detailsmultivariable logistic regression
- Multivariable logistic regression
Main finding
As reported in the abstract
Moderate to severe disability
20
19.8%
Steinbrocker functional classification > class I
17.9%
Articular damage
37
36.6%
Extra-articular complications
24.8%
Observational data: associations, not effects.
Further findings
Independent predictors of articular damage (multivariable logistic regression)
| aOR (95% CI) | P value | ||
|---|---|---|---|
| Steinbrocker functional classification > class I | 18.1 (3.9–84.6) | P < 0.001 | |
| Delayed diagnosis ≥ 6 months | 8.5 (2.7–27.0) | P < 0.001 | |
| ERA | 5.7 (1.8–18.3) | P = 0.004 | |
| 0.050.21520Adjusted odds ratio (log scale) |
Independent predictor of extra-articular damage
| aOR (95% CI) | P value | ||
|---|---|---|---|
| Systemic corticosteroids use | 3.8 (1.3–11.1) | P = 0.013 | |
| 0.050.21520Adjusted odds ratio (log scale) |
Extra-articular complications by type
- Growth failure and striae (most common)
- 7.8%
- Leg-length discrepancy
- 5.0%
- Ocular damage
- 1 patient with enthesitis-related arthritis (ERA)
Delayed diagnosis ≥ 6 months
- Delayed diagnosis ≥ 6 months
- 33 (32.7%)
Original publication
Disability and disease-related damage in Thai children and adolescents with juvenile idiopathic arthritis. Pediatr Rheumatol Online J. Published 10 July 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →