Rheumatoid arthritis

Mapping the bare area and transcortical pores in finger joints: co-location with bone erosions in rheumatoid arthritis

RMD OpenPublished Cross-sectional study

Authors' conclusion

These findings support the bare areas, but not transcortical pores, as structural determinants for erosion location in finger joints in RA.

Study context

Population
Finger joints of deceased individuals obtained postmortem, and patients with rheumatoid arthritis (RA)
Participants
8 vs 22
Exposure
Postmortem vs RA
  • Postmortemn = 8
  • RAn = 22
Outcome
Number, size and spatial distribution of transcortical pores and extent of bare areas; anatomical relationship of RA erosions to bare areas
Methodological detailsdescriptive, postmortem micro-CT and histology, HR-pQCT in patients with RA
  • Descriptive
  • Postmortem micro-CT and histology
  • HR-pQCT in patients with RA

Main finding

As reported in the abstract

In RA, all erosions confined to or overlapping with the bare areas
26

Observational data: associations, not effects.

Original publication

Mapping the bare area and transcortical pores in finger joints: co-location with bone erosions in rheumatoid arthritis. RMD Open. Published 22 January 2026. doi:10.1136/rmdopen-2025-006371

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