Spondyloarthritis & psoriatic arthritis
Lower total cholesterol and triglyceride levels in ankylosing spondylitis than non-inflammatory rheumatic disease controls in a 1978-98 study: a potential effect of increased physical energetics in manual occupations in the pre-2000 chronologic era
Authors' conclusion
In the 1978-98 survey, AS had significantly lower mean serum cholesterol and triglyceride levels than NIRD control patients.
Study context
- Population
- Ankylosing spondylitis (AS) patients and matched rheumatic disease controls, USA, 1978–98 and 2000–10 surveys69 matched pairs (1978–98)
- Comparison
- AS vs matched NIRD controls
- ASn = 69
- NIRDn = 69reference
- Outcome
- Serum lipid levels in AS vs control rheumatic disorders
Methodological detailsmatched within 5 years of age, sex, and clinic or hospital source, two survey periods (1978-98 and 2000-10)
- Matched within 5 years of age, sex, and clinic or hospital source
- Two survey periods (1978-98 and 2000-10)
Main finding
As reported in the abstract
Entry serum cholesterol (mg/dL), 1978-98 survey
P < 0.001
Observational data: associations, not effects.
Further findings
| Outcome | AS | NIRD | P value |
|---|---|---|---|
| Serum cholesterol (mg/dL) in manual labour workers, 1978-98 (subgroup, 29 pairs)AS vs NIRD · mean, mg/dL | 156.7 (SE 5.9) | 213.3 (SE 8.6) | P < 0.001 |
| Serum triglyceride in manual labour workers, 1978-98 (subgroup)AS vs NIRD · 15 AS vs 14 NIRD · mean | 110.3 (SE 14.1) | 185.2 (SE 19.3) | P = 0.004 |
Serum lipids, 2000-10 survey
- No lipid difference between AS vs NIRD
Original publication
Lower total cholesterol and triglyceride levels in ankylosing spondylitis than non-inflammatory rheumatic disease controls in a 1978-98 study: a potential effect of increased physical energetics in manual occupations in the pre-2000 chronologic era. Clin Exp Rheumatol. Published 30 December 2023. doi:10.
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