Lupus & antiphospholipid syndrome
Loneliness and social isolation among middle-aged and older adults with SLE: a single centre cross-sectional study
Authors' conclusion
Lack of social connectedness is associated with decreased HRQoL in middle-aged and older adults with SLE.
Study context
- Population
- Adults ≥50 years with validated SLE
- Participants
- 80 adults
- Outcome
- Associations of loneliness, social isolation and social support with health-related quality of life (HRQoL) patient-reported outcome (PROs) (pain interference, depression, disability) and frailty
Methodological detailssingle-centre, survey
- Single-centre
- Survey
Main finding
As reported in the abstract
Associations of social measures with PROs, adjusted for age, race, ethnicity, disease activity and organ damage
- Social measures significantly correlated (r −0.89 to 0.66)
- all P < 0.01
- Greater loneliness and social isolation independently associated with greater pain, depression, disability and frailty
- P = 0.04 to P < 0.01
- Greater social support associated with less pain, depression, disability and frailty after covariate adjustment
- P = 0.04 to P < 0.01
Observational data: associations, not effects.
Original publication
Loneliness and social isolation among middle-aged and older adults with SLE: a single centre cross-sectional study. Rheumatology (Oxford). Published 20 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →